Topical diphenyl diselenide mice research

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August undefined, 2024

WebThe present study evaluated the comparative toxicological effects of diphenyl diselenide (PhSe) 2 and diphenyl ditelluride (PhTe) 2 in mice after in vivo administration. … WebAug 13, 2013 · A later study of the latter research group showed that daily treatment with diphenyl diselenide (5 lmol/kg) prevented MeHg-induced brain mitochondrial dysfunction, oxidative stress and reduction ...

Investigations into the potential neurotoxicity induced by …

WebMice were pretreated with Se-PTC (1–50 mg/kg), via the peroral route (p.o), 0.5 h before injection with acetate. Control animals received a similar volume of the vehicle (10 ml/kg, canola oil) as the negative, or Celecoxib(150 mg/kg,p.o.)asthepositivecontrol.Post-challenge,the mice were placed individually into separate boxes and the total WebThe aim of this study was to verify the effect of diphenyl diselenide (PhSe) 2 on hepatic nucleotidases and on the concentration of purines in mice infected by Toxoplasma gondii. … is bing friends with google

Diphenyl Ditelluride: Redox-Modulating and Antiproliferative ... - Hindawi

WebJan 20, 2024 · It was observed that diphenyl diselenide was less toxic in rats than in mice—the LD 50 of this compound was 374.4 mg/kg in rats and 65.52 mg/kg in mice after … Weboxyl-diphenyl diselenide, (p-Cl-C H Se) – p-chloro-diphenyl dise-lenide, (PhSe) – diphenyl diselenide, PTZ – pentylenetetra zole) Introduction Among the different neurological disorders that affect the human condition, epilepsy has been largely stud-ied during the last century [16, 27] and has become a dynamic research field in recent ... WebDiphenyl diselenide-modulation of macrophage activation: Down-regulation of classical and alternative activation markers Lucı´a L Rupil1,2, Andreza F de Bem2 and German A Roth1 Abstract Diphenyl diselenide (PhSe) 2, a simple organoselenium compound, possesses interesting pharmacological properties that are under extensive research. is bing good now reddit

Diphenyl diselenide improves scopolamine-induced memory impairment in mice

Diphenyl diselenide derivatives inhibit microbial biofilm …

WebDec 11, 2013 · The acute liver failure (ALF) induced by acetaminophen (APAP) is closely related to oxidative damage and depletion of hepatic glutathione, consequently changes in cell energy metabolism and mitochondrial dysfunction have been observed after APAP overdose. Diphenyl diselenide [(PhSe)2], a simple organoselenium compound with … WebApr 18, 2024 · Methylmercury (MeHg) is a ubiquitous and persistent environmental pollutant that induces serious neurotoxic effects. Diphenyl diselenide [(PhSe)2], an organoseleno … is bing going to be better than google is bing going to use chat

"WebAbstract. In the current study, nanocapsules (NC) formulations containing a co-load of clotrimazole (C), a highly prescribed antifungal drug, and diphenyl diselenide [(PhSe) 2], an organoselenium compound with a promising scope of pharmacological actions, were prepared.Formulations were characterized as well as the potential toxicity, antioxidant … " - Topical diphenyl diselenide mice research

Topical diphenyl diselenide mice research

Investigations into the potential neurotoxicity induced by …

WebDiphenyl diselenide is used in the methoxyselenenylation of alkenes, dihydroxylation of double bonds, hydrothiolation of terminal alkynes. It is used in the synthesis of the … WebApr 1, 2024 · Here, we addressed the pharmacology and toxicology of synthetic organoselenium compounds and some naturally occurring organoselenium amino acids. The use of selenium as a tool in organic synthesis and as a pharmacological agent goes back to the middle of the nineteenth and the beginning of the twentieth centuries. The …

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WebAug 13, 2013 · A later study of the latter research group showed that daily treatment with diphenyl diselenide (5 lmol/kg) prevented MeHg-induced brain mitochondrial dysfunction, … WebOct 1, 2024 · Moreover, topical treatment with the hydrogel containing (OMePhSe) 2 loaded-nanocapsules was more effective in reducing ear thickness and the inflammatory …

WebFeb 1, 2003 · Administration of 200 μmol/kg diphenyl diselenide (i.p.) induced 100% seizures in mice and caused 50% death in 72 h. All mice died after doses higher than 350 μmol/kg of diphenyl diselenide. At lower doses (25–150 μmol/kg), no seizures were observed. The LD 50 calculated and the 95% confident interval was 210 μmol/kg … WebAug 1, 2016 · Diphenyl Diselenide Reduces Oxidative Stress and Toxicity Caused by HSV-2 Infection in Mice: Diphenyl diselenide decreases HSV-2 toxicity August 2016 Journal of …

WebOct 28, 2010 · Since the successful use of the organoselenium drug ebselen in clinical trials for the treatment of neuropathological conditions associated with oxidative stress, there … WebObjectives: This study investigated the involvement of different types of K(+) channels and PPARgamma receptors in the antidepressant-like effect of diphenyl diselenide in mice. Methods: Mice were pretreated with subeffective doses of K(+) channel inhibitors (tetraethylammonium, glibenclamide, charybdotoxin and apamin), openers (cromakalim, …

WebOct 24, 2024 · Tellurium is a rare element that has been regarded as a toxic, nonessential element, and its biological role is not clearly established. In addition, the biological effects of elemental tellurium and some of its organic and inorganic derivatives have been studied, leading to a set of interesting and promising applications. Diphenyl ditelluride (DPDT), an …

WebFeb 1, 2003 · Administration of 200 μmol/kg diphenyl diselenide (i.p.) induced 100% seizures in mice and caused 50% death in 72 h. All mice died after doses higher than 350 … is bing good for privacyWebJan 1, 2024 · The current study investigated the effect of organoselenium compound p,p′-methoxyl-diphenyl diselenide [(OMePhSe) 2], free or incorporated into nanocapsules, on behavioral, biochemical and molecular alterations in an inflammatory pain model induced by complete Freund's adjuvant (CFA). Male Swiss mice received an intraplantar injection of … is bingham plastic a newtonian fluidWebSep 21, 2016 · Research article; Open Access; Published: ... The prevention of biofilm formation is the goal of wound treatment because the standard protocols based on … is bing good search engineWebDec 25, 2024 · Exposure to pesticide chlorpyrifos (CPF) is associated with neurodevelopmental toxicity both in humans and animals. Diphenyl diselenide (DPDS) is a … is bing google chromeWebBisphenol A (BPA) is a chemical toxicant that has deleterious effects on human. BPA causes oxidative stress in tissues, including the liver. Diphenyl diselenide (PhSe) 2 improves the antioxidant response via activation of the nuclear factor (erythroid-derived 2)-like 2 (Nrf2)/Kelch-like ECH-associated protein (keap 1) pathway in macrophage cells. In the … is bing gpt better than chat gptWebAldrich-180629; Diphenyl diselenide 0.98; CAS No.: 1666-13-3; Synonyms: Phenyl diselenide; Linear Formula: C6H5SeSeC6H5; Empirical Formula: C12H10Se2; find related products, papers, technical documents, MSDS & more at Sigma-Aldrich. ... Our team of scientists has experience in all areas of research including Life Science, Material Science, ... is bing google ownedWebAug 25, 2024 · Diphenyl diselenide was effective against 32 Aspergillus isolates (MIC 64 µg mL −1 ), which increased the fungicidal action of the drug caspofungin, but was ineffective against an aspergillosis ... is bing hacked