WebCD226 antigen. DNAX accessory molecule 1. DNAM-1. CD_antigen=CD226. Background Information. CD226/DNAM1 is a T cell expressed plasma membrane receptor protein that plays multiple roles in lymphocyte signaling, intercellular adhesion, lymphokine secretion and cytotoxic T-cell and NK cell mediated killing. Web性质:又称内皮细胞黏附分子-1。. 由589个氨基酸组成,分子量115000。. 仅表达于内皮细胞的选择素。. 内皮细胞在受到细胞因子 (如TNF-α、IL-1等)或内毒素的刺激后,迅速合成E选择素并转移到内皮细胞的管腔面。. 它通过与唾液酸化路易斯糖 (s-Lex)及其同类异构物 ...
PD-1与PD-L1有什么区别 - 百度知道
WebThe present invention addresses the problem of providing a novel preventive or therapeutic agent to prevent/treat idiopathic inflammatory myopathy effectively and safely. An antibody or an antibody fragment which specifically binds to DNAM-1 and does not bind to an Fc receptor is used as the active ingredient of the preventive or therapeutic agent for … Web26-28 与 tigit 结合相反,cd155/pvr 或 cd112 对 dnam-1/cd226 的活化可促进 cd8 + t 细胞和 nk 细胞的细胞毒性和细胞因子生成,并且抑制肿瘤生长。 26, 29 因此,dnam-1/cd226 和 tigit 代表对 t 细胞和 nk 细胞活性有相反影响的成对受体,与 cd28 和 ctla-4 成对受体系统相似 … bins cc server
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WebFeb 8, 2015 · Anti-DNAM-1 monoclonal antibody does not protect from the development of collagen-induced arthritis at clinical assessment. (a) Clinical evidence of arthritis with … WebJun 24, 2024 · DNAM-1 (CD226) ist das Akronym für „ DNX-Accessory Molecule-1 “. DNAM-1 ist ein Zelloberflächen-Glykoprotein, das als Adhäsionsmolekül fungiert. Nach Kommunikation mit aktivierenden Rezeptoren steuert DNAM-1 über die Zytotoxizität von NK-Zellen die Interferon-γ -Produktion gegen eine Vielzahl von Pathogenen (Martinet L … http://immuno-tsukuba.com/research/dnam-1.html bins cc telegram