Cub domain-containing protein

WebOct 3, 2024 · Abstract. Rationale: An antibody-drug conjugate (ADC) is a targeted therapy consisting of a cytotoxic payload that is linked to an antibody which targets a protein … WebCUB domain-containing protein 1 (CDCP1) is a protein that in humans is encoded by the CDCP1 gene. It has also been designated as CD318 (cluster of differentiation 318) and …

CUB Domain-Containing Protein 1 (CDCP1) Is a Target for …

WebMar 28, 2011 · Signal peptide-CUB-EGF-like domain-containing protein 3 (SCUBE3) is a secreted glycoprotein that is overexpressed in lung cancer tumor tissues and is correlated with the invasive ability in a lung ... WebJun 1, 2008 · One such antigen, CUB domain-containing protein 1 (CDCP1), was recognized by monoclonal antibody 25A11 and is a single transmembrane molecule highly expressed in several metastatic cancers as well ... trust distribution to children https://60minutesofart.com

CUB and zona pellucida-like domain-containing protein 1 …

WebAug 1, 2009 · The function of CUB domain-containing protein 1 (CDCP1), a recently described transmembrane protein expressed on the surface of hematopoietic stem cells and normal and malignant cells of different tissue origin, is not well defined. The contribution of CDCP1 to tumor metastasis was analyzed by using HeLa carcinoma cells … WebMar 23, 2024 · The structure of CUB domains consists of a beta-sandwich with a jelly-roll fold. Almost all CUB domains contain four conserved cysteines that probably form two … WebCUB domain-containing protein 1 (CDCP1) is a substrate of Src family kinases and has been shown to regulate anoikis resistance, migration and matrix degradation during tumor invasion and metastasis in a tyrosine phosphorylation-dependent manner. philipp thomann

Structural Requirements for Cub Domain Containing Protein 1

Category:CUB and zona pellucida-like domain-containing protein 1 …

Tags:Cub domain-containing protein

Cub domain-containing protein

Entry - *611735 - CUB DOMAIN-CONTAINING PROTEIN 1; CDCP1 …

WebSep 1, 2009 · CUB and sushi domain-containing protein 3. Alternative names. CUB and sushi multiple domains protein 3; Gene names. Name. CSMD3. Synonyms. KIAA1894. Organism names. Organism. Homo sapiens (Human) Taxonomic identifier. 9606 NCBI. Taxonomic lineage. WebDec 7, 2004 · PTHR24251:SF37 CUB DOMAIN-CONTAINING PROTEIN 2 1 hit; PTHR24251 OVOCHYMASE-RELATED 1 hit; PROSITE. View protein in PROSITE; PS01180 CUB 3 hits; Pfam. View protein in Pfam; PF00431 CUB 3 hits; SMART. View protein in SMART; SM00042 CUB 3 hits; SUPFAM. SSF49854 Spermadhesin, CUB …

Cub domain-containing protein

Did you know?

WebOct 1, 2024 · CUB domain-containing protein 1 (CDCP1) is one of the few transmembrane glycoprotein that contains three extracellular CUB domains and … WebOct 2, 2024 · Comment: annotation includes both PSPI/PSPII interaction residues highlighted. Download Cn3D for Viewing 3D Structure Scroll to Sequence Alignment …

WebCUB domain-containing protein 1 (CDCP1) is a protein that in humans is encoded by the CDCP1 gene. It has also been designated as CD318 (cluster of differentiation 318) and Trask (Transmembrane and associated with src kinases). CDCP1/Trask is a 140kD transmembrane glycoprotein with a large extracellular domain (ECD) containing two … WebLaw, M. E., Ferreira, R. B., Davis, B. J., Higgins, P. J., Kim, J.-S., Castellano, R. K., … Law, B. K. (2016). CUB domain-containing protein 1 and the epidermal ...

WebJan 7, 2024 · Signal peptide-CUB-EGF domain-containing protein 3 (SCUBE3) is a member of a small family of multifunctional cell surface-anchored glycoproteins functioning as co-receptors for a variety of growth factors. ... Ugef, and Bmp1 (CUB)-epidermal growth factor (EGF)-like domain-containing (SCUBE) protein family comprises three related … WebNational Center for Biotechnology Information

WebOct 1, 2024 · CUB domain-containing protein 1 (CDCP1) is a transmembrane glycoprotein that contains three extracellular CUB domains and regulates anchorage …

WebDec 3, 2012 · Specific cleavage of the transmembrane molecule, CUB domain-containing protein-1 (CDCP1), by plasmin-like serine proteases induces outside–in signal transduction that facilitates early stages of ... philipp thomasWebCUB domain-containing protein 1 (CDCP1) is a protein that in humans is encoded by the CDCP1 gene. CDCP1 has also been designated as CD318 (cluster of differentiation … philipp thomas hotelfriendWebJul 10, 2012 · The deduced 993-amino acid protein has an N-terminal signal sequence, followed by 9 putative calcium-binding EGF-like repeats, a spacer region, and a C-terminal CUB domain. The spacer region contains 5 potential N-glycosylation sites. SCUBE3 was predicted to be secreted as a mature 971-amino acid protein with a calculated molecular … trust distribution to foreign beneficiaryWebMay 21, 2024 · The role of CDCP1 (CUB domain-containing protein 1) and ADAM12 (a disintegrin and metalloproteinase 12) in ovarian cancer. J BUON. 2015;20(3):673–679. 16. Miura S, Hamada S, Masamune A, et al. CUB-domain containing protein 1 represses the epithelial phenotype of pancreatic cancer cells. trust dividend rates 2022/23WebJul 27, 2011 · CUB and sushi domain-containing protein 1. Gene. Csmd1. Status. UniProtKB reviewed (Swiss-Prot) Organism. Mus musculus (Mouse) Amino acids. 3564. Protein existence. Evidence at protein level. Annotation score. 5/5. Entry. Feature viewer. Publications. External links. History. BLAST Align. Download. Add Add a publication … trust doba 2 in 1 home office setWebSummary. This gene encodes a transmembrane protein which contains three extracellular CUB domains and acts as a substrate for Src family kinases. The protein plays a role in the tyrosine phosphorylation-dependent regulation of cellular events that are involved in tumor invasion and metastasis. philipp thomas bellmontWebDec 31, 2012 · Cub domain containing protein 1 (CDCP1) is strongly expressed in tumors derived from lung, colon, ovary, or kidney. It is a membrane protein that is phosphorylated and then bound by Src family … trust dividend tax rates