Cilastatin molecular weight
WebA method for providing a passivation layer or pH protective coating on a substrate surface by PECVD is provided, the method comprising generating a plasma from a gaseous reactant comprising polymerizing gases. The lubricity, passivation, pH protective, hydrophobicity, and/or barrier properties of the passivation layer or pH protective coating are set by … WebCombination of imipenem and cilastatin that is used in the treatment of bacterial infections; cilastatin inhibits renal dehydropeptidase I to prolong the half-life and increase the tissue penetration of imipenem, enhancing its efficacy as an anti-bacterial agent. ... Molecular Formula. C12-H17-N3-O4-S.C16-H26-N2-O5-S. Molecular Weight. 657.8057 ...
Cilastatin molecular weight
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WebCilastatin is excreted primarily in unchanged form in the urine, but about 12% of the drug appears as the metabolite N-acetylcilastatin [ 485 ]. In neonatal studies, the intravenous … WebCilastatin UNII 141A6AMN38 Molecular formula C 16 H 26 N 2 O 5 S Molecular weight 358.45 Percent composition C 53.61%, H 7.31%, N 7.82%, O 22.32%, S 8.94% …
WebCilastatin ammonium salt United States Pharmacopeia (USP) Reference Standard Empirical Formula (Hill Notation): C16H26N2O5S · NH3 CAS Number: 877674-82-3 … WebFeb 15, 2016 · Antimicrobial stewardship programs (ASPs) focus on improving the utilization of broad spectrum antibiotics to decrease the incidence of multidrug-resistant Gram positive and Gram negative pathogens. Hospital admission for both medical and surgical intra-abdominal infections (IAIs) commonly results in the empiric use of broad spectrum …
WebFeb 1, 2024 · It is an off-white, nonhygroscopic crystalline compound with a molecular weight of 317.37. It is sparingly soluble in water and slightly soluble in methanol. Its … WebIt is an off-white, nonhygroscopic crystalline compound with a molecular weight of 317.37. It is sparingly soluble in water and slightly soluble in methanol. Its empirical formula is C 12 H 17 N 3 O 4 S•H 2 O, and its structural formula is: Cilastatin sodium is the sodium salt of a derivatized heptenoic acid.
WebAug 20, 2024 · It is an off-white, nonhygroscopic crystalline compound with a molecular weight of 317.37. It is sparingly soluble in water, and slightly soluble in methanol. Its …
WebMolecular Formula: C 16 H 26 N 2 O 5 S Molecular Weight: 358.45 Percent Composition: C 53.61%, H 7.31%, N 7.82%, O 22.32%, S 8.94% pop up children\u0027s bookWebCilastatin sodium salt (≥ 98% HPLC); Cilastatin sodium salt is off-white to yellowish-white, hygroscopic, amorphous compound; Inhibitor of dehydropeptidase I; Inhibitor of the renal … pop up children\u0027s booksWebApr 15, 2024 · Her treatment with unspecified low molecular weight heparin was discontinued and she started receiving treatment with acenocoumarol. Within the third … sharon ledwith athenryWebFigure 1: Imipenem molecular structure (molecular weight = 299.347 grams/mole). Figure 2: Cilastatin molecular structure (molecular weight = 358.454 grams/mole). Meropenem Meropenem is a derivative of thienamycin. It does not require co-administration with cilastatin because it is not sensitive to renal dipeptidase. sharon lee ciprianiWebAdditional Names: Cilastatin sodium Molecular Formula: C16H25N2NaO5S Molecular Weight: 380.43 Percent Composition: C 50.51%, H 6.62%, N 7.36%, Na 6.04%, O 21.03%, S 8.43% Properties: Off-white to yellowish-white hygroscopic, amorphous solid. pKa1 2.0; pKa2 4.4; pKa3 9.2. Very sol in water, methanol. pKa: pKa1 2.0; pKa2 4.4; pKa3 9.2 pop up children\u0027s play tentWebFeb 28, 2024 · Cilastatin was administered subcutaneously to rats (GD 6 to 17) and intravenously to rabbits (GD 6 to 18) at doses up to 1000 and 300 mg/kg/day, respectively, approximately 3.2 and 1.9 times the RHD (based on body surface area). ... It is an off-white to yellowish-white, hygroscopic, amorphous compound with a molecular weight of … pop up child\u0027s tentpopup child